Applications for Equine Research Fellows being accepted through Aug. 1
Applications for the 2013 American Association of Equine Practitioners (AAEP) Foundation Past Presidents’ Research Fellow and EQ... More »
Bramlage Serving as On Call Veterinarian for Belmont Telecast
Larry Bramlage, DVM, will return to the role of AAEP On Call veterinarian when he assists NBC Sports with horse health informati... More »
Dr. Scott Palmer to Serve as AAEP On Call Veterinarian for Preakness Weekend Telecasts
Scott Palmer, VMD, will assist NBC Sports with horse health info... More »
Dr. Mary Scollay to Step in as AAEP On Call Veterinarian for Oaks, Derby
Longtime AAEP On Call Veterinarian Mary Scollay will serve as the spokesperson for equine health during NBCSports racing coverag... More »
Statement from the AAEP regarding the Injury to On Call Veterinarian Dr. Larry Bramlage
Dr. Larry Bramlage injured his head Thursday afternoon in a fall from a golf cart in the barn area of Churchill Downs. He was tr... More »
Summer Education Meetings to Provide New Knowledge to Practitioners of All Experience Levels
The American Association of Equine Practitioners’ 2013 series of summer continuing education meetings will impart the latest tre... More »
Vaccination and Passive Transfer
It is important to vaccinate broodmares 4 to 6 weeks before foaling for their own protection, as well as to maximize concentrations of immunoglobulins in their colostrum to be passively transferred to their foals. The significant majority of vaccines used in broodmares during late gestation to maximize immunoglobulin transfer via the colostrum do not carry a “safe for use in pregnant mare” claim. However, this is an accepted practice and clinical experience indicates these products are safe for this purpose, but if the practitioner has specific safety questions or concerns, he or she is encouraged to contact he manufacturer for additional information.
Recognize that simply vaccinating the mare is not sufficient for protection of the foal; successful passive transfer must also occur. The foal must receive adequate amounts of high quality colostrum and absorb adequate amounts of specific colostral immunoglobulins before absorption of macromolecules ceases (generally 24 to 48 hours). Specific colostral immunoglobulins provide protection against field infections for several months but also may interfere with vaccinal antigens and may interfere with foal responses to vaccines; a phenomenon termed “maternal antibody interference.”
Although protective concentrations of maternal antibody decline with time, vaccination of a foal while these colostral antibodies are present - even at concentrations less than those considered to be protective - is often of minimal value because of maternal antibody interference. Consequently, a foal may be susceptible to infection before the primary vaccinal series is completed. Management directed at minimizing exposure to infectious agents is key during this interval.
Foals with residual maternal antibodies generally produce a greater serologic response to killed vaccines when an initial series of three doses is administered rather than the 2-dose series recommended by most manufacturers of vaccines for older horses without residual maternal antibodies.
©Copyright AAEP 2012
American Association of Equine Practitioners